OPEN ACCESS SPONSOR: RAREi, a collaboration of innovative pharmaceutical companies focused on the development of medicines for rare disorders, including Alexion Pharma Canada Corp., Amicus Therapeutics Canada Inc., Biogen Canada Inc., Biomarin Pharmaceutical Inc., Horizon Therapeutics Canada, Ipsen Biopharmaceuticals Canada Inc., Mitsubishi Tanabe Pharma Canada, Recordati Rare Disease Canada Inc., Sobi Canada Inc., Ultragenyx Pharmaceutical Inc., and Vertex Pharmaceuticals (Canada) Inc.